![]() ![]() For women, the loss is between 1.0 year (3.0%) and 1.6 years (4.8%) of life expectancy. Men with elevated relative mortality risk (for the remainder of their lives) of 19% lose between 1.1 years (3.7%) and 1.7 years (5.7%) of normal life expectancy. However, life expectancy for 30-year-old men is only 8% less than for women age 30.Ĭonsider 50-year-old men and women and first assume that mortality relative risk is 1.19 due to consumption of 45-64 g of alcohol per day. Mortality relative risk is approximately 1.67 for men in comparison to women between ages 30 and 70, and relative risk is 1.30 for ages 70 to 100. We know that elevated mortality risk means shorter life expectancy, but the quantitative effect is far from obvious.2 Differences between elevated mortality risk and percentage losses in life expectancy can be dramatic and unintuitive.3 For example, consider 30-year-old men and women. find statistically significant mortality relative risk of 1.19 for people consuming 45-64 grams of alcohol per day and relative risk of 1.35 for 65 or more g per day.1 How are patients to interpret these relative risks? It would be natural to ask a physician what consuming these quantities of alcohol means in terms of diminished life expectancy. In their meta-analysis, Jinhui Zhao et al. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.Mean Relative Risk (RR) Estimates of All-Cause Mortality Due to Alcohol Consumption up to 2022 for Subgroups (Cohorts Recruited 50 Years of Age or Younger and Followed up to 60 Years of Age) Statistical Analysis of Unadjusted Mean Relative Risk (RR) of All-Cause Mortality for Different Categories of Drinkers for Testing Publication Bias and Heterogeneity of RR Estimates From Included StudiesĮTable 3. Unadjusted, Partially Adjusted, and Fully Adjusted Relative Risk (RR) of All-Cause Mortality for Drinkers (vs Nondrinkers), 1980 to 2022ĮTable 2. Relative Risk (95% CI) of All-Cause Mortality Due to Any Alcohol Consumption Without Any Adjustment for Characteristics of New Studies Published between 20ĮFigure 4. Funnel Plot of Log-Relative Risk (In(RR)) of All-Cause Mortality Due to Alcohol Consumption Against Inverse of Standard Error of In(RR)ĮFigure 3. Newly Included 20 Studies (194 Risk Estimates) of All-Cause Mortality and Consumption in 2015 to 2022ĮFigure 2. ![]() Flowchart of Systematic Search Process for Studies of Alcohol Consumption and Risk of All-Cause MortalityĮTable 1. Methodology of Meta-analysis on All-Cause Mortality and Alcohol ConsumptionĮFigure 1. ![]()
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